Susan Hasty, Publisher
Table of Contents . . . November 16th, 2006
Non-Subscriber - Summaries OnlyRelated Areas: Other Issues in Gene Therapy Weekly | Other Publications
Cancer Gene Therapy - Medulloblastoma gene therapy delivered by human neural stem cells
Genetics & Genomics - Alternative splicing regulator identified by an expression cloning strategy
Pain Management - Neuropathic pain alleviated by injection of antisense oligonucleotides
RNA Interference - RNA interference library based on nuclear receptor consensus sequences reported
Vector Development - Lentiviral in situ vector delivery enabled gene transfer into adult stem cells
Angiogenesis - New angiogenesis findings from Children's Hospital described
Cancer Gene Therapy - Data on cancer gene therapy discussed by researchers at Ruhr University, Institute of Microbiology and Hygiene
Cancer Gene Therapy - Recent studies from Swiss Federal Institute of Technology, Department of Chemistry and Applied Biosciences add new data to cancer gene therapy
Cancer Gene Therapy - Research from Center for Cancer Research in the area of cancer gene therapy published
Cancer Gene Therapy - Researchers from National Institutes of Health describe findings in cancer gene therapy
Cancer Gene Therapy - Scientists at University of Alabama, Gene Therapy Center release new data on cancer gene therapy
DNA Vaccines - Research on DNA vaccines described by scientists at West Virginia University, Department of Obstetrics and Gynecology
Gene Therapy - Data on gene therapy described by researchers at Cornell University, Department of Genetic Medicine
Gene Therapy - Data on gene therapy published by researchers at Pennsylvania State University, Department of Chemistry
Gene Therapy - Investigators at Hawaii Agriculture Research Center publish new data on gene therapy
Gene Therapy - Investigators at Peking University, Institute of Sports Medicine target gene therapy
Gene Therapy - Investigators at University of Minnesota, Institute for Molecular Virology publish new data on gene therapy
Gene Therapy - New gene therapy data have been reported by scientists at University of Arizona, Department of Molecular and Cellular Biology
Gene Therapy - New gene therapy research from Medical College of Wisconsin, Department of Microbiology and Molecular Genetics discussed
Gene Therapy - New gene therapy research from National Institute of Agrobiological Science, Department of Developmental Biology outlined
Gene Therapy - New gene therapy study findings have been reported by researchers at Maine Medical Center
Gene Therapy - New gene therapy study findings have been reported from Georgetown University, Department of Biochemistry
Gene Therapy - New gene therapy study findings have been reported from SAIC-Frederick, Inc.
Gene Therapy - Recent findings from University of California, Cardiovascular Research Institute highlight research in gene therapy
Gene Therapy - Reports outline gene therapy research from Kyowa Hakko Kogyo Co., Ltd.
Gene Therapy - Research from Cornell University, Department of Microbiology and Immunology yields new findings on gene therapy
Gene Therapy - Research from Nankai University, College of Life Sciences has provided new data on gene therapy
Gene Therapy - Research from University of Queensland, Division of Molecular Genetics and Development has provided new data on gene therapy
Gene Therapy - Research on gene therapy published by scientists at University of Georgia
Gene Therapy - Researchers at Searle, Department of Medicine release new data on gene therapy
Gene Therapy - Researchers from Naval Health Research Center, Research Department publish new studies and findings in the area of gene therapy
Gene Therapy - Researchers' work from Cardiff University, Department of Rheumatology focuses on gene therapy
Gene Therapy - Scientists at University of Innsbruck, Institute of Pharmacy publish research in gene therapy
Gene Therapy - Studies from Roche describe new findings in gene therapy
Gene Therapy - Study findings from Ohio State University, Center for Retrovirus Research broaden understanding of gene therapy
Gene Therapy - Study results from McGill University, McGill Cancer Center broaden understanding of gene therapy
Hepatocellular Cancer Prevention - New findings from Johns Hopkins University in the area of hepatocellular cancer prevention published
Hepatocellular Cancer Therapy - Studies from Sungkyunkwan University, Division of Gastroenterology yield new information about hepatocellular cancer therapy
Lymphoma Gene Therapy - Findings from Medical University of Vienna, Division of Oncology advance knowledge in lymphoma gene therapy
Prostate Cancer Therapy - Research reports from Cardiff University provide new insights into prostate cancer therapy
Quantitative PCR Assays - Researchers from University of Missouri, Department of Molecular Microbiology and Immunology provide details of new studies and findings in the area of quantitative PCR assays
Allergy & Immunology - Allergic asthma is not modulated by ADAM33
Allergy & Immunology - Structure and function of the long pentraxin PTX3 glycosidic moiety examined
Apoptosis - Apoptosis genes regulated by Wnt/beta-catenin pathway identified
Apoptosis - Beta-cell death is regulated by nuclear factor-KB
Apoptosis - Early apoptotic genes targeted in batch and fed-batch CHO cell cultures
Bladder Cancer - Macrophage cytotoxicity against bladder cancer cells involves cytokines
Brain Cancer - Glioma-produced extracellular matrix influences brain tumor tropism of neural stem cells
Breast Cancer - Vector-activated dendritic cell injection and chemotherapy suppresses breast cancer
Business & Finance - Enzo Biochem reports results for fiscal 2006 and fourth quarter
Business Update - Compugen discloses status of in silico-discovered therapeutic candidates
Business Update - D-Pharm to join NeuroNE Network of Excellence
Business Update - Dow Neurobiology Laboratories extends their MetaCore licenses from GeneGo
Business Update - Enzo Biochem acquires license to six key RNA amplification patents
Cancer Gene Therapy - Antitumor effect enhanced by vaccination with telomerase reverse transcriptase modified tumor cell
Cancer Gene Therapy - Cancer cell gene expression changes following human papillomavirus integration
Cancer Gene Therapy - Controlled suicide gene system selectively kills human umbilical vein endothelial cells
Cancer Gene Therapy - Hepatocarcinoma gene therapy inhibiting NF-kappa B results in apoptosis
Cancer Gene Therapy - Introgen: Advexin molecular targeted therapy is active in multiple cancers
Cancer Gene Therapy - Myeloid progeny cell cytoskeleton reconstituted by retroviral-aided gene transfer
Cancer Immunotherapy - Lentigen gets SBIR to evaluate lentiviral-engineered T cells for cancer immunotherapy
Cancer Prevention - Cancer preventive ellagic acid accumulates in digestive tract epithelial cells
Cancer Therapy - Biological functions of a possible tumor suppressor characterized
Cancer Therapy - Effect of protein loss on spontaneous gynecological tumor development clarified
Cancer Therapy - Liver cancer cell interferon-mediated inhibition varies in different cell lines
Cancer Vaccine - Tumor-associated antigen-specific DNA vaccine induces protective and therapeutic antitumor immunity
Carcinoid Tumors - Carcinoid tumors could potentially be treated by targeted inhibition of protein kinase D family
Cardiology - Neointimal growth after vascular injury requires protein kinase C
Cell Biology - Receptor-based mobilization of internal calcium assayed
Cell Physiology - Cell polarity and focal adhesion turnover regulated in migrating cells
Cell Physiology - Nucleoporin is required for nuclear protein export
Chronic Liver Disease - Fatty liver disease and liver cirrhosis role of adiponectin clarified
Critical Care Medicine - Response to recombinant factor VIIa predicted patients with severe hemorrhage
Dermatology - Fabry disease sympathetic skin responses improved by enzyme replacement therapy
Diabetes Control - Diabetic beta cells are destroyed by cytotoxic T cells
Diabetes Control - Diabetic nephropathy genetically controlled in a mouse model
Diabetes Pathogenesis - Insulin-like growth factor receptor functions in kinase phosphorylation
DNA Research - Duplex formation improves radiolabeled antisense DNA delivery in cell cultures
DNA Research - Horizontally acquired DNA identified by interpolated variable order motifs
DNA Research - Noncoding Y RNAs are required for human chromosomal DNA replication
DNA Research - Structure of T4 pyrimidine dimer glycosylase defined
Drug Development - Exelixis files IND application for XL281 anticancer compound
Endocrinology - Neuroendocrine cell type-specific expression of the chromogranin B gene defined
Enzymology - Ubiquitin ligases are found in a novel complex that is recruited to targets
Facilities - Texas Children's Hospital announces largest investment ever by single pediatric organization
Finance - Inovio Biomedical closes $15.25 million equity financing
Finance - Senesco Technologies announces completion of $2.3 million equity financing
Finance - Senesco Technologies reports fiscal 2006 $3,314,885 net loss compared to $2,978,918 in 2005
Gastroenterology - Contribution of carboxylesterase isozymes to intestinal hydrolase activity clarified
Gastroenterology - Sterol transfer reconstituted by half-transporters
Gene Repair - Knowledge of mechanisms of action at molecular level lacking for targeted gene repair
Gene Research - 454 Sequencing reveals a new pathway in RNA interference
Gene Therapy - Inovio gets $1.1M from U.S. DoD to apply gene delivery technology to biodefense-related vaccines
Gene Therapy Policy - Policymaking process in Japan for gene therapy is appraised
Genetics & Genomics - Expression profiling identifies pathways altered in cellular immortalization
Genetics & Genomics - Genomic identification of regions of unusual compositional properties reported
Helicobacter Pylori - Helicobacter protein expression correlates with gastric adenocarcinoma
Hepatitis B Virus - Hepatitis B antigens are targeted differentially by monoclonal antibodies
Hepatitis C Virus - Hepatitis C virus replication targeting achieved with a single lentiviral vector
Hepatoma - Morris hepatoma cell apoptosis genes are induced by angiopoietin overexpression
Hepatoma - Morris hepatoma growth and vascularization inhibited by troponin overexpression
HIV/AIDS Prevention - HIV-1 integrase activity inhibited by synthetic peptides
HIV/AIDS Testing - HIV protease inhibitors screened by cytotoxicity protection
Imaging - Imaging of caspase activation in apoptosis reported
Infectious Diseases - Fabry disease protects against enterohemorrhagic Escherichia coli
Infectious Diseases - Human brucellosis displays cytokine gene polymorphisms
Infectious Diseases - Infection-related intestinal epithelial tight junction integrity studied
Licensing Agreements - Clinical Data signs exclusive license for monoclonal antibody pharmacogenetic patent portfolio
Licensing Agreements - Debiopharm and Cambridge Antibody Technology to develop and market gastric carcinoma therapy
Lung Cancer - Non-small cell lung cancer treated using cytotoxic agents
Malaria - Plasmodium falciparum soluble histo-aspartic protease partial characterized
Market Analysis - Discover applications of microarrays in pharmaceutical arena with new report
Market Analysis - Report urges integrating pharmacokinetic and pharmacodynamic concepts into biotech drug development
Mergers & Acquisitions - Inovio acquires rights to DNA vaccine licenses and intellectual property from Valentis
Mesothelioma Vaccine - Mesothelioma is targeted with infectivity-enhanced survivin/conditionally replicative adenoviruses
Muscular Dystrophy - Muscular dystrophy associated-protein emerin is phosphorylated on Ser 49 by protein kinase A
Nanotechnology - Nanoparticle system achieves RNA interference
Neuroscience - Axonal sensorimotor polyneuropathy is associated with leader peptide mutation
Neuroscience - Cultured hippocampal neuron glycosylation is altered by ethanol
Neuroscience - Drosophila odorant response requires nervous system expression of beta integrin gene
Neuroscience - Epilepsy-linked receptor function is alleviated by phenobarbital
Neuroscience - Juvenile neuronal ceroid lipofuscinosis autoantibody response patterned
Neuroscience - Kallikrein participates dynamically in traumatic spinal cord injury
Neuroscience - Neural progenitor proliferation increased by protein overproduction
Neuroscience - Neural regeneration protein is a neuronal survival-promoting factor
Neuroscience - Overstimulation of prion protein signaling pathways injures neuronal cells
Neuroscience - Selective action of ifenprodil at the N-methyl-D-aspartate receptor probed
Neuroscience - Tau protein sequential phosphorylation generates a filamentous epitope
Pancreatic Cancer Treatment - Early immunization promotes lifelong control of pancreatic tumor progression
Pancreatic Cancer Treatment - p53-derived peptide blocks pancreatic cancer cell growth
Patents - Dyadic granted patent for high-throughput screening of expressed DNA libraries in filamentous fungi
Personnel - Enzo Biochem appoints former Novartis Pharmaceutical executive president of Enzo Therapeutics
Proteomics - High abundance proteins profiled in cystic fibrosis lung epithelial cells
Proteomics - Protein computational design stereochemically optimized
Proteomics - Rab5 stimulates insulin receptor substrate-protein kinase interaction
Proteomics - Recombinant activin A purified using follistatin gene domain
Respiratory Medicine - Binding site for Moraxella catarrhalis protein identified
Rett Syndrome - Case School of Medicine professor discovers nerve cell defects caused by mental retardation gene
Spinal Cord Injury - Sangamo collaborator reports positive preclinical data from nerve regeneration program
Toxicology - Molecular targets against mustard toxicity identified
Transplant Medicine - CD4+ T cells stimulated by adenovirus peptides recognize cells infected with adenovirus
Vector Development - Integration profile of equine infectious anemia virus-based vectors is presented
Virology - Herpes simplex virus type 1 nuclear capsid egress reconstituted in vitro
Virology - Retrovirus involved in tumor progression studied in vivo
Virology - Virus invasion of host cells identities a novel role for caveolae
Angiogenesis - New angiogenesis research reported from St. Michael's Hospital, Division of Cardiology
Antisense Technology - Investigators at Miami University, Department of Zoology have published new data on antisense technology
Antisense Technology - New findings from State University of Campinas describe advances in antisense technology
Biochemistry - Data on biochemistry reported by researchers at University of Ferrara, Department of Biochemistry and Molecular Biology
Biotechnology - Reports summarize biotechnology research from Agricultural Biotechnology Center
Cancer Gene Therapy - Dankook University, Institute of Nanosensor and Biotechnology details research in cancer gene therapy
Cancer Gene Therapy - Data on cancer gene therapy published by researchers at Second Military Medical University
Cancer Gene Therapy - Data on cancer gene therapy reported by researchers at University of Texas, M.D. Anderson Cancer Center
Cancer Gene Therapy - Research conducted at Kyoto University has provided new information about cancer gene therapy
Cancer Gene Therapy - Research on cancer gene therapy detailed by scientists at Ordway Research Institute, New York State Department of Health
Cancer Gene Therapy - Researchers from National Cheng-Kung University, Institute of Clinical Medicine detail findings in cancer gene therapy
Cancer Gene Therapy - Scientists at University of Kuopio, Department of Biotechnology and Molecular Medicine describe research in cancer gene therapy
Cancer Gene Therapy - Scientists at Yamaguchi University, Department of Obstetrics and Gynecology detail research in cancer gene therapy
Gene Therapy - Findings from National Heart and Lung Institute, Faculty of Medicine in gene therapy reported
Gene Therapy - Research on gene therapy reported by scientists at National Institute for Longevity Science
Gene Therapy - Studies from Max Delbruck Center for Molecular Medicine further understanding of gene therapy
Microbiological Methods - Osaka University reports research in microbiological methods
RNA Research - Studies from University of Antwerp in the area of RNA research published
Angiology - Researchers in the United States, Taiwan and Germany zero in on angiology
Apoptosis - New apoptosis study findings have been reported from Canada and the United States
Apoptosis - New findings from the United States and United Kingdom describe advances in apoptosis research
Apoptosis - Research from Germany, the United States and Italy yields new apoptosis data
Breast Cancer - Recent findings in breast cancer described by researchers from University of Texas, U.S.
Breast Cancer - Reports from the United States and Greece add new data to breast cancer research
Breast Cancer - Reports outline breast cancer research from Wayne State University, U.S.
Cancer Treatment - New cancer treatment study findings reported from University of Texas, U.S.
Cancer Treatment - Research from University of Michigan, U.S., provides new data about cancer treatment
Cancer Treatment - Studies from Fourth Military Medical University, People's Republic of China, reveal new findings on cancer treatment
Cardiology - Research in the area of cardiology reported from the United States and United Kingdom
Cardiology - Studies in the area of cardiology reported from the United States, Switzerland and Germany
Genetics - Research from Innsbruck University, Austria, in the area of genetics discussed
Genetics - Study findings from University of Helsinki, Finland, provide new insights into genetics
Ischemia - Findings from Japan in ischemia research reported
Neurology - Studies in the area of neurology reported from Fudan University, People's Republic of China
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