Antisense Technology
New findings from State University of Campinas describe advances in antisense technology
Published in Gene Therapy Weekly, November 16th, 2006
A report, "Phosphoinositide-specific inositol polyphosphate 5-phosphatase IV inhibits inositide trisphosphate accumulation in hypothalamus and regulates food intake and body weight," is newly published data in Endocrinology. According to recent research from Brazil, "The enzyme phosphatidylinositol 3-kinase (PI3-kinase) exerts an important role in the transduction of the anorexigenic and thermogenic signals delivered by insulin and leptin to first-order neurons of the arcuate nucleus in the hypothalamus. The termination of the intracellular signals generated by the activation of PI3-kinase depends on the coordinated activity of specific inositol phosphatases."
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Source: Gene Therapy Weekly (2006-11-16)
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