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HIV/AIDS Vaccines

Reports summarize HIV/AIDS vaccines study results from Center for Cancer Research

Published in Gene Therapy Weekly, November 30th, 2006

Data detailed in "An adenovirus-based HIV subtype B prime/boost vaccine regimen elicits antibodies mediating broad antibody-dependent cellular cytotoxicity against non-subtype B HIV strains" have been presented. "Although HIV subtype B predominates in North America and Western Europe, most HIV infections worldwide are non-subtype B. Globally effective AIDS vaccines need to elicit broad immunity against multiple HIV strains," scientists in the United States report.

"In this study, 10 chimpanzees were intranasally primed sequentially with adenovirus type 5 (Ad5)-and Ad7-HIVMNenv/rev recombinants and boosted twice intramuscularly with heterologous oligomeric HIVSF162...

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