Ovarian Cancer
Data on ovarian cancer published by researchers at New York University
Published in Gene Therapy Weekly, December 14th, 2006
Data detailed in "Inhibition of matrilysin expression by antisense or RNA interference decreases lysophosphatidic acid-induced epithelial ovarian cancer invasion" have been presented. According to recent research published in the journal Molecular Cancer Research, "Our previous reports show that matrilysin [matrix metalloproteinase (MMP)-7] is overexpressed in epithelial ovarian cancer (EOC) and recombinant MMP-7 promotes EOC invasion in vitro. In the present study, we further evaluated the correlation of MMP-7 expression to EOC invasiveness and examined its role in lysophosphatidic acid (LPA)-induced invasion."
"By sense and antisense gene transfection in vitro,...
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Source: Gene Therapy Weekly (2006-12-14)
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