DNA Vaccines
Researchers from National Taiwan Ocean University, Department of Food Science publish new studies and findings in the area of DNA vaccines
Published in Gene Therapy Weekly, December 14th, 2006
New investigation results, "Development of an effective Japanese encephalitis virus-specific DNA vaccine," are detailed in a study published in Microbes and Infection. According to a study from Keelung, Taiwan, "Intramuscular immunization with DNA vaccines has been shown to induce a broad range of immune responses and protective immunity in many animal models, but it is less effective in primates. One reason for this may be the low expression of vector-encoded antigen in cells."
"Here we report that the use of vaccine vector (pCJ-3) containing two regulatory elements, a chimeric intron and a bovine growth hormone (BGH) polyadenylation signal, markedly increased antigen...
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Source: Gene Therapy Weekly (2006-12-14)
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