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DNA Vaccines

University of Bonn describes research in DNA vaccines

Published in Gene Therapy Weekly, December 21st, 2006

Fresh data on dna are presented in the report "Evaluation of DNA vaccination with recombinant adenoviruses using bioluminescence imaging of antigen expression: impact of application routes and delivery with dendritic cells." According to recent research from Germany, "Recombinant DNA vaccines are able to induce strong CD8+ T cell mediated immunity and have become increasingly attractive for the prevention and treatment of infectious diseases and cancer. Dendritic cells (DC), which critically control cellular immune responses, have been transduced with antigen ex vivo and used as 'nature's adjuvant' to enhance vaccine efficacy."

"The impact of the application route on...

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