Biological Chemistry
Study results from Carnegie Mellon University, Department of Biological Sciences broaden understanding of biological chemistry
Published in Gene Therapy Weekly, December 28th, 2006
Research findings, "Sequence-specific interactions in the RNA-binding domain of Escherichia coli transcription termination factor Rho," are discussed in a new report. According to recent research published in the Journal of Biological Chemistry, "Rho factor is an essential protein that causes termination of transcription in a wide variety of bacteria by an RNA-dependent helicase activity. Rho is activated by transcripts that contain a high proportion of cytidine residues."
"The interaction between Rho and two adjacent cytidine residues within the bound RNA has been identified by previous crystallographic studies (Skordalakes, E., and Berger, J. M. (2003) Cell...
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Source: Gene Therapy Weekly (2006-12-28)
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