Gene Therapy
Researchers from Beth Israel Deaconess Medical Center, Division of Viral Pathogenesis detail new studies and findings in the area of gene therapy
Published in Gene Therapy Weekly, January 4th, 2007
New research, "Immunogenicity of heterologous recombinant adenovirus prime-boost vaccine regimens is enhanced by circumventing vector cross-reactivity," is the subject of a report. "The high prevalence of preexisting immunity to adenovirus serotype 5 (Ad5) in human populations has led to the development of recombinant adenovirus (rAd) vectors derived from rare Ad serotypes as vaccine candidates for human immunodeficiency virus type 1 and other pathogens. Vaccine vectors have been constructed from Ad subgroup B, including rAd11 and rAd35, as well as from Ad subgroup D, including rAd49," scientists in the United States report.
"However, the optimal combination of vectors...
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Source: Gene Therapy Weekly (2007-01-04)
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