Cancer Gene Therapy
Researchers at University of Padua, Department of Pharmaceutical Sciences have published new data on cancer gene therapy
Published in Gene Therapy Weekly, January 11th, 2007
Research findings, "Synthesis and biological in vitro evaluation of novel PEG-psoralen conjugates," are discussed in a new report. "Psoralens are well-known photosensitizers, and 8-methoxypsoralen and 4,5',8-trimethylpsoralen are widely used in photomedicine as "psoralens plus UVA therapy" (PUVA), in photopheresis, and in sterilization of blood preparations. In an attempt to improve the therapeutic efficiency of PUVA therapy and photopheresis, four poly(ethylene glycol) (PEG)-psoralen conjugates were synthesized to promote tumor targeting by the enhanced permeability and retention (EPR) effect," scientists in Padova, Italy report.
"Peptide linkers were used to exploit...
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Source: Gene Therapy Weekly (2007-01-11)
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