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Cancer Gene Therapy

Recent studies from Institute of Immunology add new data to cancer gene therapy

Published in Gene Therapy Weekly, January 18th, 2007

Data detailed in "Down-regulation of Bcl-XL by RNA interference suppresses cell growth and induces apoptosis in human esophageal cancer cells" have been presented. In this recent report, researchers in Nanchong, People's Republic of China conducted a study "To determine the inhibitory effect of the vector-generated small interfering RNAs (siRNAs) on the expression of the Bcl-X(L) gene in established human esophageal cancer cells, and to investigate the effect of the Bcl-X(L) siRNAs on cell growth and apoptosis in esophageal cancer cells. Three siRNA-expressing vectors targeting different sites of the Bcl-X(L) gene were constructed from pTZ-U6+1 vector."

"Cultured...

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