Cancer Gene Therapy
Researchers from Hektoen Institute for Medical Research, Medical Research Division detail findings in cancer gene therapy
Published in Gene Therapy Weekly, January 18th, 2007
A new study, "Bispecific antisense oligonucleotides with multiple binding sites for the treatment of prostate tumors and their applicability to combination therapy," is now available. According to a study from the United States, "Antisense oligonucleotides (oligos) against transforming growth factor-alpha (TGF-alpha; MR(1)) and its binding site, the epidermal growth factor receptor (EGFR; MR(2)), have proven efficacious against PC-3 and LNCaP prostate tumors when evaluated in both in vitro and in vivo models. To enhance their activity, and also to introduce a significantly different type of multifunctional agent into this field, "bispecific" oligos were constructed containing truncated...
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Source: Gene Therapy Weekly (2007-01-18)
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