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Gene Therapy

Reports from the United States, Japan and Germany describe recent advances in gene therapy research

Published in Gene Therapy Weekly, February 15th, 2007

Data on gene therapy are outlined in reports from the United States, Japan and Germany.

Study 1: Investigators publish new data in the report "Complete correction of murine Artemis immunodeficiency by lentiviral vector-mediated gene transfer. Artemis gene mutations are responsible for the development of a severe combined immunodeficiency [radiation-sensitive (RS) SCID] characterized by a severe B and T cell deficiency and a normal natural killer cell population. To establish the feasibility of a gene therapy approach to the treatment of RS-SCID, we generated a series of lentiviral vectors expressing human Artemis from different promoters and used them to transduce...

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