Gene Therapy
Scientists at University of Maryland, Institute for Physical Science and Technology discuss research in gene therapy
Published in Gene Therapy Weekly, March 1st, 2007
Investigators publish new data in the report "Mechanical unfolding of RNA: from hairpins to structures with internal multiloops." According to a study from the United States, "Mechanical unfolding of RNA structures, ranging from hairpins to ribozymes, using laser optical tweezer experiments have begun to reveal the features of the energy landscape that cannot be easily explored using conventional experiments. Upon application of constant force (f), RNA hairpins undergo cooperative transitions from folded to unfolded states whereas subdomains of ribozymes unravel one at a time."
"Here, we use a self-organized polymer model and Brownian dynamics simulations to probe...
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Source: Gene Therapy Weekly (2007-03-01)
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