Cancer Gene Therapy
Research results from Second Military Medical University, Gene Therapy Center update knowledge of cancer gene therapy
Published in Gene Therapy Weekly, March 8th, 2007
A new study, "CpG island methylator phenotype association with elevated serum alpha-fetoprotein level in hepatocellular carcinoma," is now available. According to recent research published in the journal Clinical Cancer Research, "CpG island methylator phenotype (CIMP) involves hypermethylation targeted toward the promoters of multiple genes. To gain insight into the role of epigenetic aberration of tumor-related genes in hepatocarcinogenesis, we determined a hypermethylation profile in hepatocellular carcinoma (HCC)."
"We examined the promoter methylation status of nine genes in 50 HCCs, 50 paired nontumor tissues, and 6 normal liver tissues by...
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Source: Gene Therapy Weekly (2007-03-08)
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