Gene Therapy

Studies from Yale University, Department of Medicine describe new findings in gene therapy

Published in Gene Therapy Weekly, March 8th, 2007

A new study, "Hormonal regulation of nuclear permeability," is now available. "Transport into the nucleus is critical for regulation of gene transcription and other intranuclear events. Passage of molecules into the nucleus depends in part upon their size and the presence of appropriate targeting sequences," scientists in the United States report.

"However, little is known about the effects of hormones or their second messengers on transport across the nuclear envelope. We used localized, two-photon activation of a photoactivatable green fluorescent protein to investigate whether hormones, via their second messengers, could alter nuclear permeability. Vasopressin and...

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Source: Gene Therapy Weekly (2007-03-08)

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