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DNA Vaccines

Hokkaido University publishes research in DNA vaccines

Published in Gene Therapy Weekly, March 15th, 2007

Research findings, "A novel DNA vaccine targeting macrophage migration inhibitory factor protects joints from inflammation and destruction in murine models of arthritis," are discussed in a new report. According to a study from Sapporo, Japan, "Previous studies have demonstrated that neutralization of macrophage migration inhibitory factor (MIF) by anti-MIF antibodies decreases joint inflammation and destruction in a type II collagen-induced arthritis model in mice. The aim of this study was to develop and describe a simple and effective method of active immunization that induces anti-MIF autoantibodies, which may neutralize MIF bioactivity."

"We developed a MIF DNA...

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