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Cancer Gene Therapy

Scientists at Okayama University detail research in cancer gene therapy

Published in Gene Therapy Weekly, April 12th, 2007

Researchers detail in "Novel cell-surface peptides specific to human oral squamous cell carcinoma using an E. coli peptide display library," new data in cancer gene therapy. According to recent research from Okayama, Japan, "We attempted to find a specific antigen of oral squamous cell carcinoma (SCC) cells that could be safely applied to gene therapy in the conservative clinical treatment of oral cancer. We performed subtraction using normal human keratinocyte cells, followed by selection using four oral SCC cell lines."

"We isolated three clones from poorly differentiated SCC cells and four from well-differentiated SCC cells. These seven clones adsorbed to the oral...

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