Gene Therapy
Studies from Harvard University, CBR Institute for Biomedical Research in the area of gene therapy published
Published in Gene Therapy Weekly, April 12th, 2007
A report, "Selective gene silencing in activated leukocytes by targeting siRNAs to the integrin lymphocyte function-associated antigen-1," is newly published data in Proceedings of the National Academy of Sciences of the United States of America. "Silencing gene expression by RNAi is a powerful method for exploring gene function and validating drug targets and potentially for therapy. Lymphocytes and other primary blood cells are resistant to lipid-based transfection in vitro and are difficult to target in vivo," researchers in the United States report.
"We show here that antibody-protamine fusion proteins targeting the human integrin lymphocyte...
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Source: Gene Therapy Weekly (2007-04-12)
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