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Gene Therapy

Studies from University of Coimbra, Center for Neuroscience and Cell Biology provide new data on gene therapy

Published in Gene Therapy Weekly, April 26th, 2007

Data detailed in "siRNA delivery by a transferrin-associated lipid-based vector: a non-viral strategy to mediate gene silencing" have been presented. "RNA interference provides a powerful technology for specific gene silencing. Therapeutic applications of small interfering RNA (siRNA) however require efficient vehicles for stable complexation, protection, and extra-and intracellular delivery of these nucleic acids," scientists writing in the Journal of Gene Medicine - Gene Therapy Clinical Trial Database report.

"Here, we evaluated the potential of transferrin (Tf)-associated liposomes for siRNA complexation and gene silencing. Cationic liposomes composed of...

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