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Gene Therapy

Researchers at Lund University, Wallenberg Neuroscience Center target gene therapy

Published in Gene Therapy Weekly, April 26th, 2007

Fresh data on gene therapy are presented in the report "Ngn2 and Nurr1 act in synergy to induce midbrain dopaminergic neurons from expanded neural stem and progenitor cells. Parkinson's Disease (PD) is a debilitating motor function disorder due primarily to a loss of midbrain dopaminergic neurons and a subsequent reduction in dopaminergic innervation of the striatum. Several attempts have been made to generate dopaminergic neurons from progenitor cell populations in vitro for potential use in cell replacement therapy for PD," scientists in Lund, Sweden report.

"However, expanding cells from fetal brain with retained potential for dopaminergic differentiation has proven...

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