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Prostate Cancer Genetics

Research from University of Southern California, Institute for Genetic Medicine yields new findings on prostate cancer genetics

Published in Gene Therapy Weekly, May 3rd, 2007

Research findings, "Insulin growth factor-binding protein 2 is a candidate biomarker for PTEN status and PI3K/Akt pathway activation in glioblastoma and prostate cancer," are discussed in a new report. "PTEN is an important tumor-suppressor gene associated with many cancers. Through expression profiling of glioblastoma tissue samples and prostate cancer xenografts, we identified a molecular signature for loss of the PTEN tumor suppressor in glioblastoma and prostate tumors," researchers in the United States report.

"The PTEN signature consists of a minimum of nine genes, several of which are involved in various pathways already implicated in tumor formation. Among these...

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