Cancer Gene Therapy
Gelatin-Based Nanoparticle Effective in Gene Therapy for Breast Cancer
Published in Gene Therapy Weekly, May 3rd, 2007
Northeastern University professor Mansoor Amiji and graduate student Sushma Kommareddy have published a new paper that examines the potential of engineered gelatin-based nanoparticles to deliver therapeutic genes to human breast cancer tumors implanted in mice. Their research shows that these nanoparticles – or nanovectors – can serve as a safe and effective gene delivery vehicle to inhibit solid tumor growth. The paper is published in the most recent issue of Cancer Gene Therapy.
In the experiment, the nanoparticles were injected into the blood stream, and 15% of the dose found its way into the tumor, where it produced a protein, sFlt-1 or soluble receptor for an...
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Source: Gene Therapy Weekly (2007-05-03)
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