Research from Taipei Veterans General Hospital provide new insights into gene therapy

New research, "Evaluation of anti-Fas ligand-induced apoptosis and neural differentiation of PC12 cells treated with nerve growth factor using small interfering RNA method and sampling by microdialysis," is the subject of a report. According to a study from Taipei, Taiwan, "The small interfering RNA (siRNA) method is an effective technique for silencing gene expression and is a useful tool for screening the gene functions in drug discovery. Our study found that nerve growth factor (NGF) can increase the cell viability of PC12 cells and that NGF induction up-regulates the expression of Bcl-2 detected by real-time reverse transcription-polymerase chain reaction (RT-PCR)."

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