Gene Therapy
Studies from Okayama University reveal new findings on gene therapy
Published in Gene Therapy Weekly, May 17th, 2007
Fresh data on gene therapy are presented in the report "Leucyl/phenylalanyl(L/F)-tRNA-protein transferase-mediated aminoacyl transfer of a nonnatural amino acid to the N-terminus of peptides and proteins and subsequent functionalization by bioorthogonal reactions." According to recent research from Okayama, Japan, "We report here a new strategy for derivatizing peptides and proteins at the N-terminus. To achieve this, a nonnatural amino acid was charged onto a tRNA and then enzymatically transferred to a lysine (Lys) unit at the N-terminus of a peptide or a protein by using L/F-tRNA-protein transferase."
"By using the chemoenzymatic technique,...
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Source: Gene Therapy Weekly (2007-05-17)
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