Study data from Tokai University, Department of Pathology provide new insights into gene therapy

Data detailed in "Granulogenesis in non-neuroendocrine COS-7 cells induced by EGFP-tagged Chromogranin A gene transfection: identical and distinct distribution of CgA and EGFP" have been presented. According to a study from Isehara, Japan, "We examined whether an enhanced green fluorescent protein (EGFP)-tagged chromogranin A (CgA) gene construct could serve as a marker protein to follow the synthesis of CgA and the process of granulogenesis in non-neuroendocrine (NE) cells. We transfected a CgA-EGFP expression vector into non-NE COS-7 cells and investigated the localization of a chimeric CgA-EGFP protein using confocal laser scanning microscopy (CLSM)."

"The...

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