Gene Therapy
Studies in the area of gene therapy reported from University of Sao Paulo, Center for Gene Therapy
Published in Gene Therapy Weekly, May 24th, 2007
Researchers detail in "Cloning and characterization of an alternative splicing transcript of the gene coding for human cytidine deaminase," new data in gene therapy. "Human cytidine deaminase (HCD) catalyzes the deamination of cytidine or deoxycytidine to uridine or deoxyuridine, respectively. The genomic sequence of HCD is formed by 31 kb with 4 exons and several alternative splicing signals, but an alternative form of HCD has yet to be reported," scientists in Sao Paulo, Brazil report.
"Here we describe the cloning and characterization of a small form of HCD, HSCD, and it is likely to be a product of alternative splicing of HCD. The alignment of DNA sequences shows...
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Source: Gene Therapy Weekly (2007-05-24)
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