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Gene Therapy

Recent findings from Yale University highlight research in gene therapy

Published in Gene Therapy Weekly, May 31st, 2007

Research findings, "A noncoding RNA in Saccharomyces cerevisiae is an RNase P substrate," are discussed in a new report. "Ribonuclease P (RNase P) is involved in regulation of noncoding RNA (ncRNA) expression in Saccharomyces cerevisiae. A hidden-in-reading-frame antisense-1 (HRA1) RNA in S. cerevisiae, which belongs to a class of ncRNAs located in the antisense strand to verified protein coding regions, was cloned for further use in RNase P assays. Escherichia coli RNase P assays in vitro of HRA1 RNA show two cleavage sites, one major and one minor in terms of rates," investigators in the United States report.

"The same result was observed with a...

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