Gene Therapy
Reports from Friedrich-Schiller University Jena advance knowledge in gene therapy
Published in Gene Therapy Weekly, May 31st, 2007
Investigators publish new data in the report "Regulatory mechanisms employed by cis-encoded antisense RNAs. Bacterial small regulatory RNAs that act by base-pairing can be divided into two classes: cis-encoded and trans-encoded antisense RNAs. The former--mainly discovered in plasmids, phages and transposons--are encoded in the same DNA locus and are therefore completely complementary to their targets over a long sequence stretch," scientists in Jena, Germany report.
"Regulatory mechanisms employed by these RNAs encompass inhibition of primer maturation or RNA pseudoknot formation, transcriptional attenuation, inhibition of translation or promotion of RNA degradation or...
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Source: Gene Therapy Weekly (2007-05-31)
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