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Gene Therapy

Researchers Awaken Vision Cells in Blind Mice

Published in Gene Therapy Weekly, June 7th, 2007

University of Florida researchers used gene therapy to restore sight in mice with a form of hereditary blindness, a finding that has bearing on many of the most common blinding diseases.

Writing online in the May 21 edition of Nature Medicine, scientists describe how they used a harmless virus to deliver corrective genes to mice with a genetic impairment that robs them of vision.

The discovery shows that it is possible to target and rescue cone cells — the most important cells for visual sharpness and color vision in people.

“Cone vision defines whether someone is blind or not,” said William W. Hauswirth, Ph.D., the...

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