Gene Therapy

New findings from Korea Research Institute of Bioscience and Biotechnology in the area of gene therapy described

Published in Gene Therapy Weekly, June 7th, 2007

Data detailed in "Sensitization of vascular smooth muscle cell to TNF-alpha-mediated death in the presence of palmitate" have been presented. "Saturated free fatty acids (FFAs), including palmitate, can activate the intrinsic death pathway in cells. However, the relationship between FFAs and receptor-mediated death pathway is still unknown," researchers in Korea report.

"In this study, we have investigated whether FFAs are able to trigger receptor-mediated death. In addition, to clarify the mechanisms responsible for the activation, we examined the biochemical changes in dying vascular smooth muscle cell (VSMC) and the effects of various molecules to the...

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Source: Gene Therapy Weekly (2007-06-07)

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