Gene Therapy
Reports outline gene therapy study results from Boston University, Department of Medicine
Published in Gene Therapy Weekly, June 7th, 2007
New investigation results, "A novel fur- and iron-regulated small RNA, NrrF, is required for indirect fur-mediated regulation of the sdhA and sdhC genes in Neisseria meningitidis," are detailed in a study published in Journal of Bacteriology. "Iron is both essential for bacterial growth and toxic at higher concentrations; thus, iron homeostasis is tightly regulated. In Neisseria meningitidis the majority of iron-responsive gene regulation is mediated by the ferric uptake regulator protein (Fur), a protein classically defined as a transcriptional repressor," scientists writing in the Journal of Bacteriology report.
"Recently, however, microarray...
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Source: Gene Therapy Weekly (2007-06-07)
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