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Retinoblastoma Cell Biology

Research from Hiroshima University, Department of Neurosurgery in the area of retinoblastoma cell biology published

Published in Gene Therapy Weekly, June 21st, 2007

Current study results from the report, "Retinoblastoma protein prevents staurosporine-induced cell death in a retinoblastoma-defective human glioma cell line," have been published. In this recent report, researchers in Japan conducted a study "To investigate the mechanism of staurosporine-induced glioma cell death and cell cycle arrest using adenovirus-mediated gene transfection, as well as the function of retinoblastoma (Rb) and genetic instability induced by staurosporine. Cell cycle regulation, cell death and nuclear abnormalities induced by staurosporine were examined using an adenovirus vector expressing Rb, p16 or p21 genes in human glioma cell lines."

"The...

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