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Gene Therapy

Scientists at University of Helsinki, Institute of Biomedicine detail research in gene therapy

Published in Gene Therapy Weekly, June 28th, 2007

A new study, "An adenosine triphosphatase of the sucrose nonfermenting 2 family, androgen receptor-interacting protein 4, is essential for mouse embryonic development and cell proliferation," is now available. According to recent research published in the journal Molecular Endocrinology, "An adenosine triphosphatase of the sucrose nonfermenting 2 protein family, androgen receptor-interacting protein 4 (ARIP4), modulates androgen receptor activity. To elucidate receptor-dependent and -independent functions of ARIP4, we have analyzed Arip4 gene-targeted mice."

"Heterozygous Arip4 mutants were normal. Arip4 is expressed mainly in the neural tube and limb buds during...

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