Cancer Gene Therapy

Bacteria ferry nanoparticles into cells for early diagnosis, treatment

Published in Gene Therapy Weekly, June 28th, 2007

Researchers at Purdue University have shown that common bacteria can deliver a valuable cargo of "smart nanoparticles" into a cell to precisely position sensors, drugs or DNA for the early diagnosis and treatment of various diseases.

The approach represents a potential way to overcome hurdles in delivering cargo to the interiors of cells, where they could be used as an alterative technology for gene therapy, said Rashid Bashir, a researcher at Purdue's Birck Nanotechnology Center.

The researchers attached nanoparticles to the outside of bacteria and linked DNA to the nanoparticles. Then the nanoparticle-laden bacteria transported the DNA to the...

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Source: Gene Therapy Weekly (2007-06-28)

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