Gene Therapy
Recent findings in gene therapy described by researchers from University of British Columbia, Life Sciences Center
Published in Gene Therapy Weekly, June 28th, 2007
Investigators publish new data in the report "Disintegrator vectors for single-copy yeast chromosomal integration. Vectors were developed for two-step chromosomal integration of reporter genes or expression constructs. With these vectors, integration produces a disruption of the ADE8, LYS2, MET15, LEU2, HIS3 or FCY1 genes, and integrants can be easily identified by replica-plating on selective media," investigators in Vancouver, Canada report.
"Integration using these 'disintegrator' vectors produces a single-copy integration of the construct of interest at the junction of the marker deletion, and removes the additional plasmid sequences. Importantly, the integrated...
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Source: Gene Therapy Weekly (2007-06-28)
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