Gene Therapy

Studies from Heinrich-Heine University, Department of Bioinformatics update current data on gene therapy

Published in Gene Therapy Weekly, July 19th, 2007

Scientists discuss in "A likelihood framework to measure horizontal gene transfer" new findings in gene therapy. "We suggest a likelihood-based approach to estimate an overall rate of horizontal gene transfer (HGT) in a simplified setting. To this end, we assume that the number of occurring HGT events within a given time interval follows a Poisson process," scientists in Dusseldorf, Germany report.

"To obtain estimates for the rate of HGT, we simulate the distribution of tree topologies for different numbers of HGT events on a clocklike species tree. Using these simulated distributions, we estimate an HGT rate for a collection of gene trees representing a set of taxa....

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Source: Gene Therapy Weekly (2007-07-19)

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