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Cancer Gene Therapy

Research on cancer gene therapy described by scientists at University of Texas, Sealy Center for Cancer Cell Biology

Published in Gene Therapy Weekly, July 26th, 2007

New research, "Up-regulation of tumor susceptibility gene 101 conveys poor prognosis through suppression of p21 expression in ovarian cancer," is the subject of a report. "The function of tumor susceptibility gene 101 (TSG101) in ovarian carcinogenesis is largely unexplored. The aim of this study is to investigate the role of TSG101 in human ovarian cancer development, to examine the expression levels of TSG101 in ovarian carcinomas, and to correlate the results with clinicopathologic variables and survival," scientists in the United States report.

"Human ovarian cancer tissue arrays that contain duplicates of 422 cases of primary ovarian carcinoma were used to probe...

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