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Cancer Gene Therapy

Studies from University of Florida, Shands Cancer Center provide new data on cancer gene therapy

Published in Gene Therapy Weekly, July 26th, 2007

Research findings, "Protein kinase C epsilon is overexpressed in primary human non-small cell lung cancers and functionally required for proliferation of non-small cell lung cancer cells in a p21/Cip1-dependent manner," are discussed in a new report. "The protein kinase C (PKC) family of proteins plays important roles in growth regulation and is implicated in tumorigenesis. It has become clear that the role of PKC in tumorigenesis is cell context dependent and/or isoform specific," scientists writing in the journal Cancer Research report.

"In this study, we showed for the first time by immunohistochemistry that overexpression of PKC epsilon was detected in the...

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