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Cancer Gene Therapy

Pure Chance or Is There a System? Computer Program to Uncover Non-Randomness in Genome Sequence Distribution

Published in Gene Therapy Weekly, July 26th, 2007

For some years now, scientists throughout the world have been in a position to use the complete base sequence of the human genome for their analyses. A question often encountered is whether or not specific sequence motifs have a special function. This is likely in cases where the motif is found in a particular place more often than mere chance distribution would suggest. So far, such calculations have only been possible using time-consuming computer simulations.

Scientists at the German Cancer Research Center (Deutsches Krebsforschungszentrum, DKFZ) and the National Center for Tumor Diseases (NCT) Heidelberg, collaborating with colleagues in Paris and London, have been...

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