Solid Cancer

Studies from A. Mengesha et al add new findings in the area of solid cancer

Published in Gene Therapy Weekly, August 2nd, 2007

According to a study from Netherlands, "Bacterial-based tumor-targeted therapy is an area of growing interest and holds promise for the treatment of solid tumors. Upon systemic administration, various types of non- pathogenic obligate anaerobes and facultative anaerobes have been shown to infiltrate and selectively replicate within solid tumors."

"The tumor specificity is based upon the unique physiology of solid tumors, which is often characterized by regions of hypoxia and necrosis. Prokaryotic vectors can be safely administered and their potential to deliver therapeutic proteins has been demonstrated in a variety of preclinical models. Although the amount of clinical...

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Source: Gene Therapy Weekly (2007-08-02)

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