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Gene Therapy

Researchers from University of California, Department of Anesthesiology report recent findings in gene therapy

Published in Gene Therapy Weekly, August 2nd, 2007

New research, "Schwann cells: activated peripheral glia and their role in neuropathic pain," is the subject of a report. According to recent research published in the journal Brain, Behavior, and Immunity, "Schwann cells provide trophic support and in some cases, insulation to axons. After injury, Schwann cells undergo phenotypic modulation, acquiring the capacity to proliferate, migrate, and secrete soluble mediators that control Wallerian degeneration and regeneration."

"Amongst the soluble mediators are pro-inflammatory cytokines that function as chemoattractants but also may sensitize nociceptors. At the same time, Schwann cells produce factors that...

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