Gene Therapy

Researchers from Shanghai Jiao Tong University detail findings in gene therapy

Published in Gene Therapy Weekly, August 16th, 2007

"A newly synthesized secretory protein in cells bears a special sequence, called signal peptide or sequence, which plays the role of ''address tag'' in guiding the protein to wherever it is needed. Such a unique function of signal sequences has stimulated novel strategies for drug design or reprogramming cells for gene therapy," investigators in Shanghai, People's Republic of China report.

"To realize these new ideas and plans, however, it is important to develop an automated method for fast and accurately identifying the signal sequences or their cleavage sites. In this paper, a new method is developed for predicting the signal sequence of a query secretory protein by...

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Source: Gene Therapy Weekly (2007-08-16)

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