HIV/AIDS

New HIV/AIDS study findings have been reported by scientists at University of Montpellier

Published in Gene Therapy Weekly, August 16th, 2007

"We have shown previously that HIV actively and selectively packages the spliced HIV RNAs into progeny virions. In the present study, by using a RT-QPCR and QPCR strategies, we show that spliced viral RNAs are present in infectious particles and consequently participate, along with the unspliced genomic RNA, to some of the early steps of infection such as the reverse transcription step," scientists in Montpellier, France report.

"This work provides the first quantitative data on reverse transcription of the fully spliced viral RNAs, also called the early transcripts, in target cells but also inside virions. The latter results were obtained by measuring the natural...

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Source: Gene Therapy Weekly (2007-08-16)

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