Gene Therapy

Data on gene therapy detailed by researchers at Peking University, National Key Laboratory of Protein Engineering and Plant Gene Engineering

Published in Gene Therapy Weekly, August 30th, 2007

New research, "Targeting matrix metalloproteinases and endothelial cells with a fusion peptide against tumor," is the subject of a report. According to recent research from People's Republic of China, "Development of novel therapy for patients with tumor is still a challenge at the present time. We designed a fusion peptide (RK5) with two targets as a novel agent against tumor."

"The fusion peptide RK5 containing the kringle 5 fragment of human plasminogen and a decapeptide (CTTHWGFTLC) was constructed and expressed in yeast. Matrix metalloproteinase (MMP) activity, proliferation, and migration of endothelial cells were examined in vitro, respectively. Angiogenesis,...

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Source: Gene Therapy Weekly (2007-08-30)

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