Gene Therapy
Researchers from National Research Council report recent findings in gene therapy
Published in Gene Therapy Weekly, September 6th, 2007
Investigators publish new data in the report "Improving AAV vector yield in insect cells by modulating the temperature after infection." According to a study from Montreal, Canada, "Vectors based on adeno-associated viruses (AAV) are sought for therapeutic gene delivery because of their ability to transduce a variety of tissues with no significant immunological response. Production using the baculovirus expression vector (BEV)/insect cell system has the potential to meet the needs for pre-clinical and clinical trials."
"In this co-infection system, three baculoviruses are used to produce the AAV vector. A strategy aimed at increasing encapsidation/maturation of the...
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Source: Gene Therapy Weekly (2007-09-06)
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