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Coumadin (warfarin) Patients Receive New FDA Information

Published in Gene Therapy Weekly, September 6th, 2007

The FDA has announced important changes in the warfarin label, recommending that a lower initial warfarin dose "should be considered for patients with certain genetic variations."

Warfarin (Coumadin) is a commonly prescribed blood thinner with an exceptionally narrow safe-dosage range that varies dramatically from patient to patient.

Historically, determining the correct dose often took multiple clinical visits and blood tests over several weeks or months. Until the correct dosing was established, patients were vulnerable to potentially deadly clotting events such as stroke, and side effects such as hemorrhages, excessive bruising or internal...

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