Bacteriology

Studies from C. Geslin et al in the area of bacteriology described

Published in Gene Therapy Weekly, September 13th, 2007

According to a study from Plouzane, France, "Only one virus-like particle (VLP) has been reported from hyperthermophilic Euryarchaeotes. This VLP, named PAV1 is shaped like a lemon and was isolated from a strain of ''Pyrococcus abyssi,'' a deep-sea isolate."

"Its genome consists of a double-stranded circular DNA of 18 kb which is also present at a high copy number (60 per chromosome) free within the host cytoplasm but is not integrated into the host chromosome. Here, we report the results of complete analysis of the PAV1 genome. All the 25 predicted genes, except 3, are located on one DNA strand. A transcription map has been made by using a reverse transcription-PCR...

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Source: Gene Therapy Weekly (2007-09-13)

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