Gene Therapy
Scientists at National University target Gene Therapy
Published in Gene Therapy Weekly, September 13th, 2007
According to recent research from Taipei, Taiwan, "A-Galactosylceramide (a-GalCer), a bioactive glycolipid isolated from the marine sponge Agelas mauritianus, is a potent immunomodulator with therapeutic potential for the treatment of autoimmune diseases and cancer. The Toll-like receptor 4 (TLR4:), one of the promising molecular targets for immune-modulating drugs, is commonly expressed in innate immune cells especially macrophages and dendritic cells."
"Currently, whether alpha-GalCer can activate TLR4 signaling pathways remains unreported. In this study, we examined the effects of alpha-GalCer and its various structural analogs, CCL-1 similar to 47, on TLR4...
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Source: Gene Therapy Weekly (2007-09-13)
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