Atomic Force Microscopy
Researchers at Institute of Genomics and Integrative Biology publish new data on atomic force microscopy
Published in Gene Therapy Weekly, September 27th, 2007
New research, "Atomic force microscopy reveals the assembly of potential DNA "nanocarriers" by poly-L-ornithine," is the subject of a report. According to recent research from Delhi, India, "Atomic force microscopy (AFM) has been used to visualize the process of condensation of plasmid DNA by poly-L-ornithine on mica surface. AFM images reveal that the transition of negatively charged DNA to condensed nanoparticles on addition of increasing amounts of positively charged poly-L-ornithine (charge ratio (Z+/Z-) varied between 0.1 and 1) at a wide range of DNA concentrations (3-20 ng/microl) occurs through formation of several distinct morphologies."
"The nature of the...
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Source: Gene Therapy Weekly (2007-09-27)
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