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Non-Small Cell Lung Cancer Therapy

Research data from L. Taillade and colleagues update understanding of non-small cell lung cancer therapy

Published in Gene Therapy Weekly, October 4th, 2007

New investigation results, "Immunohistochemichal expression of biomarkers: a comparative study between diagnostic bronchial biopsies and surgical specimens of non-small-cell lung cancer," are detailed in a study published in Annals of Oncology. "The increasing use of biomarkers as molecular determinants of responsiveness to conventional chemotherapy or molecular targeted therapy has raised the question of the reliability and reproducibility of their evaluation in bronchial biopsies as compared with corresponding resected surgical specimens. Immunohistochemical expression of five markers related to signal transduction [epidermal growth factor receptor (EGFR), phospho-Akt], cell...

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